Research reference
Semax 10mg
$78.00In stock
Specifications
- Batch
- PB-24-0863
Research profile
Classification
Synthetic ACTH(4-10) analog heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro)
Mechanism of action
Non-corticotropic ACTH(4-10) fragment extended with Pro-Gly-Pro for proteolytic stability. Research describes rapid upregulation of BDNF and its receptor TrkB in hippocampal tissue, modulation of the melanocortin system without steroidogenic activity, and effects on dopaminergic/serotonergic turnover and antioxidant enzyme expression.
Investigated research applications
- BDNF/NGF and TrkB expression profiling in neuronal cultures
- Cerebral ischemia and neuroprotection models
- Cognitive performance, attention and memory task studies in rodents
- Oxidative stress and antioxidant enzyme (SOD, catalase) assays
Commonly reported assay endpoints
Hippocampal BDNF/TrkB expressionInfarct volume in ischemia modelsLatency in maze tasksLipid peroxidation (MDA)
For laboratory research use only. Not a drug, food or cosmetic. Not for human or veterinary diagnostic or therapeutic use.