Research reference
Retatrutide
$89.95In stock
Select strength
Next-generation multi-pathway research peptide.
Research profile
Classification
Triple agonist peptide — GIP / GLP-1 / glucagon receptor
Mechanism of action
Single-molecule triagonist with balanced activity at GIP, GLP-1 and glucagon (GCGR) receptors. GLP-1 and GIP agonism drive glucose-dependent insulinotropic signaling and delayed gastric emptying, while glucagon receptor agonism is studied for increased energy expenditure and hepatic lipid oxidation.
Investigated research applications
- Receptor binding affinity and cAMP accumulation assays across GIPR/GLP-1R/GCGR
- Diet-induced obesity (DIO) rodent models of adiposity and energy expenditure
- Glycemic control and insulin secretion studies
- Hepatic steatosis and lipid metabolism models
Commonly reported assay endpoints
cAMP EC₅₀ per receptorBody composition (EchoMRI)HbA1c and fasting glucoseHepatic triglyceride content
For laboratory research use only. Not a drug, food or cosmetic. Not for human or veterinary diagnostic or therapeutic use.