MOTS-C 10mg

Classification

Mitochondrial-derived peptide (16-aa, encoded in 12S rRNA)

Mechanism of action

Acts as a mitochondrial-encoded regulator of metabolic homeostasis. Research indicates activation of the AMPK pathway via inhibition of the folate–methionine cycle and accumulation of AICAR, with nuclear translocation under metabolic stress where it regulates adaptive stress-response genes.

Investigated research applications

• Insulin sensitivity and glucose uptake assays in skeletal muscle models
• AMPK signaling and mitochondrial biogenesis studies
• Exercise capacity and metabolic flexibility models
• Age-associated metabolic decline and mitohormesis research

Commonly reported assay endpoints

For laboratory research use only. Not a drug, food or cosmetic. Not for human or veterinary diagnostic or therapeutic use.